We stopped curcumin about 6 months ago because of drooling issues. I am tempted to start again. This is the curcumin we used.
Diverse effects of a low dose supplement of lipidated curcumin in healthy middle
aged people
Journal: Nutrition
Article first published online: 26 SEPT 2012 (doi: 10.1186/1475-2891-11-79)
Robert A DiSilvestro, Elizabeth Joseph, Shi Zhao, Bomser Joshua
Abstract
Background - Curcumin extracts of turmeric are proposed to produce health benefits. To date, human
intervention studies have focused mainly on people with existing health problems given high
doses of poorly absorbed curcumin. The purpose of the current study was to check whether in
healthy people, a low dose of a lipidated curcumin extract could alter wellness-related
measures.
Methods - The present study was conducted in healthy middle aged people (40–60 years old) with a low
dose of curcumin (80 mg/day) in a lipidated form expected to have good absorption. Subjects
were given either curcumin (N = 19) or placebo (N = 19) for 4 wk. Blood and saliva samples
were taken before and after the 4 weeks and analyzed for a variety of blood and saliva
measures relevant to health promotion.
Results - Curcumin, but not placebo, produced the following statistically significant changes: lowering
of plasma triglyceride values, lowering of salivary amylase levels, raising of salivary radical
scavenging capacities, raising of plasma catalase activities, lowering of plasma beta amyloid
protein concentrations, lowering of plasma sICAM readings, increased plasma
myeloperoxidase without increased c-reactive protein levels, increased plasma nitric oxide,
and decreased plasma alanine amino transferase activities.
Background - Curcumin extracts of turmeric are proposed to produce health benefits. To date, human
intervention studies have focused mainly on people with existing health problems given high
doses of poorly absorbed curcumin. The purpose of the current study was to check whether in
healthy people, a low dose of a lipidated curcumin extract could alter wellness-related
measures.
Methods - The present study was conducted in healthy middle aged people (40–60 years old) with a low
dose of curcumin (80 mg/day) in a lipidated form expected to have good absorption. Subjects
were given either curcumin (N = 19) or placebo (N = 19) for 4 wk. Blood and saliva samples
were taken before and after the 4 weeks and analyzed for a variety of blood and saliva
measures relevant to health promotion.
Results - Curcumin, but not placebo, produced the following statistically significant changes: lowering
of plasma triglyceride values, lowering of salivary amylase levels, raising of salivary radical
scavenging capacities, raising of plasma catalase activities, lowering of plasma beta amyloid
protein concentrations, lowering of plasma sICAM readings, increased plasma
myeloperoxidase without increased c-reactive protein levels, increased plasma nitric oxide,
and decreased plasma alanine amino transferase activities.
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